Sep 3, 2009

Breathalyzer Test

A new use for breathalyzers has been developed to detect lung cancer with eighty six percent accuracy.

The device could provide an early warning system before tumors become visible in X-rays. The sensor uses gold nanoparticles to detect levels of so-called volatile organic compounds, measured in a few parts per billion, that become more elevated in cancer patients. Currently, only 15 percent of cases are discovered before the disease has begun to spread.

A team of researchers took breath samples from 56 healthy people and 40 lung cancer patients. They found 33 compounds that appeared in at least 83 percent of the cancer group, but in fewer than 83 percent of the control group.

Then they designed an assembly of chemical sensors using gold nanoparticles measuring five nanometers across. (An average strand of human hair is about 100,000 nanometers in width.)

The devices were able to "distinguish between the breath of lung cancer patients and healthy controls.

"Given the impact of the rising incidence of cancer on health budgets worldwide, the proposed technology will be a significant saving for both private and public health expenditure," they say.

Lung cancer claims some 1.3 million lives worldwide each year, accounting for nearly 18 percent of all deaths from cancer, according to the World Health Organization.

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