Like most soft drinks, 7 Up started with other ingredients than we have now. It originally contained lithium, which was widely marketed as one of a number of patent medicine products popular in the late-19th and early-20th centuries. Charles Leiper Grigg invented a formula for a lemon-lime soft drink in 1929. The product was originally named "Bib-Label Lithiated Lemon-Lime Soda", and was launched two weeks before the Wall Street Crash of 1929.
It contained the mood stabilizer lithium citrate and was marketed as a hangover cure. Its name was soon changed to 7 Up. The name is derived from the atomic mass of lithium (approximately seven daltons). Lithium citrate was removed from 7 Up's formula in 1950. It was also used in early formulations of Coke.
Lithium citrate is a chemical compound of lithium and citrate that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder. Now lithium citrate is sold as Litarex and Demalit.