According to a report published by The American Council on Science and Health, "Since the 1970s, the use of high-fructose corn syrup (HFCS) in the US food supply has increased dramatically, typically as a replacement for sucrose (table sugar) in soft drinks and many food products.
The prevalence of obesity has also increased substantially between
the 1970s and the early 2000s. Because of this coincidental timing,
HFCS has been erroneously demonized as a unique cause of the obesity
epidemic in the United States.
Sucrose and HFCS have essentially the same composition, and thus it
would be highly unlikely for them to have different effects on body
weight or metabolism. Experimental evidence, as well as analyses of
epidemiological data, indicate that sucrose and HFCS have equivalent
effects on food intake and therefore on body weight. Scientific
evidence does not support the notion that HFCS is responsible for
the American obesity epidemic."