Mar 4, 2016

Aspirin Origin

On March 6, 1899 acetylsalicylic acid, was patented by The Friedrich Bayer & Co. under the trade name Aspirin at the Imperial patent office in Berlin. For over a century, it is still one of the most effective, versatile, and commonly used medications in the world.

Its active ingredient, salicin, had been used for many centuries to alleviate pain and fever. Hippocrates is known to have used it, and it had been used in modern medicine since the 19th century. As effective as it was, willow bark and salicin were used sparingly, because the taste was so bad, its use caused a severe upset stomach, and in extreme cases could even damage a stomach.

This changed when Bayer chemist Felix Hoffman created a form of the drug that was just as effective, but much better tasting and drastically easier on the stomach. Three years after Hoffman’s death in 1949, another scientist at Bayer, Arthur Eichengrün came forward claiming responsibility for Hoffman's work.

Eichengrün, who was imprisoned in the Theresienstadt concentration camp during World War II, maintained he was denied his due because he was Jewish.

Either Hoffman or Eichengrün also perfected another medication around the same time as Aspirin. Heroin was was believed to have even greater potential. It was created to be a non-addictive alternative to morphine for such ailments as labor pains and curing heavy coughs.

When Aspirin was first recommended to Heinrich Dreser, head of the pharmacological laboratory at Bayer, he rejected it, supposedly stating “The product has no value.” Once Heroin quickly began to fall as people realized how addictive it was, he revisited his decision regarding Aspirin and it quickly became Bayer’s best selling product. After World War I, Bayer had to give up its  trademark on Aspirin as part of the Treaty of Versailles in 1919.

Aspirin sales slumped with the introduction of other over-the-counter pain relievers such as ibuprofen and acetaminophen, but sales rebounded when clinical trials showed that a small daily dose of Aspirin could lower the risk of heart attack and stroke. Today, approximately 40 billion Aspirin tablets are consumed annually.

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