Oct 6, 2017

Cancer Stages and Grades

Cancer is the name given to a collection of related diseases. In all types of cancer, some of the body’s cells begin to divide without stopping and spread into surrounding tissues.
Too many of us are aware of the prevalence of cancer in our society. Two words often come up, but are not universally understood. Staging is for the cancer itself and grade references the actual tumor. There are different grading systems for different types of cancer. For instance, there is Gleason for prostate cancer, Bloom-Richardson for breast cancer, Fuhrman for kidney cancer, etc.

Cancer stage refers to the size and/or reach of the original (primary) tumor and whether or not cancer cells have spread (metastasized) elsewhere in the body. Stages do not change from initial diagnosis, even if the cancer becomes more aggressive. This is important for consistent statistical analysis.

Stage 0 (zero) Abnormal cells are present, but have not spread to nearby tissue. Stages I, II, and III indicate cancer is present. The higher the number, the larger the cancer tumor and the more it has spread into nearby tissues. Stage IV shows the cancer has spread to distant parts of the body.
Staging is usually based on the TNM system of classifying cancer. In the TNM system, each cancer is assigned a letter or number to describe the tumor, node, and metastases. T stands for the original (primary) tumor. N stands for nodes and tells whether the cancer has spread to the nearby lymph nodes. M stands for metastasis.
Tumor grade is the description of a tumor based on how abnormal the tumor cells and tumor tissue looks under a microscope. There are four grades G1 Well differentiated (low grade), G2 Moderately differentiated (intermediate grade), G3 Poorly differentiated (high grade), and G4 Undifferentiated (high grade). Grade 3 and 4 tumors tend to grow rapidly and spread faster than tumors with a lower grade.

Low-grade cancer cells look more like normal cells and tend to grow and spread more slowly than high-grade cancer cells. Cancer grade may be used to help plan treatment and determine prognosis.
In addition, there are two tumor types, benign, such as moles and warts and malignant, where the cells invade the surrounding tissue and organs.

Generally, there are five cancer stages, four tumor grades, and two tumor types, benign and malignant. Unlike school, a high stage or grade is not good.

Sep 29, 2017

Happy Friday

Destiny is a decision.

I decided my destiny is to always celebrate a Happy Friday!

National Coffee Day

Today is National Coffee Day, go out and get a free cup of coffee today at your favorite Dunkin Donuts, Krispy Kreem, Tim Horton's, and other places - but not Starbucks.

What's in a Name, Duct Tape

It was invented by Johnson & Johnson during World War II. Their original creation for the United States military was a green waterproof tape that could be used for sealing ammunition cases to keep water out.
Soldiers soon learned the tape was good at fixing any type of rip or tear they might encounter for tents, vehicle seats, and even uniforms. After the war, returning soldiers introduced it to friends and neighbors back home.
One of the first uses for the tape was to repair or seal the ductwork in home heating and cooling systems. To match the color of ductwork, the company changed the color of the tape to silver and began to call it duct tape.
Many people believe that the tape was called duck tape, because its ability to repel water reminded of the similar property of duck feathers. There is a brand of tape named Duck tape that is sometimes confused with the original.


Duct tape comes in many different colors, although the most popular are silver and black. It is so strong, because it is made of three different layers. The bottom layer is a strong rubber-based adhesive. The middle layer is a web of cloth fabric that adds durability. The top layer is soft, waterproof plastic.

Lake Baikal

If the rest of the planet’s fresh water disappeared, there would be enough left in Lake Baikal, Russia to supply humanity for 50 years. It is world's oldest (25 million years old) and deepest (over a mile deep) freshwater lake and contains about 23% of the world's fresh surface water. In Mongolian it means "the Nature Lake." Appears the screams about running out of fresh water are a bit premature.

Alcatraz

Its name came from Spanish explorer Juan Manuel de Ayala in 1775: La Isla de los Alcatraces or "Island of the Pelicans."
In 1850, US President Fillmore converted the island to military use. A fortress was built, cannons were installed, and the West Coast's first operational lighthouse was constructed.
The US Army also began to use Alcatraz to house military prisoners. It was the perfect spot for a prison, because it was isolated and everyone assumed no prisoner could successfully escape by swimming across the frigid waters of San Francisco Bay.
During the early 1900s, military prisoners helped to build a new, 600-cell jail, as well as a hospital, cafeteria, and other prison buildings. Over time Alcatraz was transferred to the US Justice Department for use as a federal prison for prisoners too dangerous to be kept at other penitentiaries. Alcatraz usually held between 260-275 prisoners. Each prisoner had his own cell, and there was one guard for about every three prisoners.
There were 14 known escape attempts involving 36 prisoners. Of those attempting to escape, 23 were captured, six were shot and killed during their attempt, two drowned, and five went missing and were officially presumed dead.

Alcatraz was shut down during 1963, because it was too expensive to keep operating. Now it is thriving again as a tourist attraction.

Hack the Fast Food Menus

We have all heard about some secret menu items at our favorite fast food places. Did you know you can get a spam and egg McMuffin at McDonald's in Hawaii? Here is a site that shows 20 secret menus from the popular franchises. Enjoy something different to spice up your life. LINK

Piracy

Gizmodo recently reported, the European Union suppressed a 300-page study (2017 Situation Report on Counterfeiting and Privacy in the European Union). The study covered all manner of foods, drugs, goods, and services, from labels to products. Concerning digital piracy, it concluded that piracy did not harm sales of copyrighted material, including books, music, video games, and movies.


From a prosecution standpoint, one problem it found is no funds are generated when a digital game is downloaded. This shortcoming is often overcome by the sale of advertising space on illegal file-sharing sites and this process is facilitated by advertising intermediaries. This no funds process makes it difficult to follow a money stream.

Television and video broadcasts are digital and are available on a variety of platforms such as mobile phones, tablets, smart TVs, and set-top boxes. In recent years, the use of set-top boxes to access large numbers of television channels, films and other protected content has increased due to low prices, improving quality of services, reliability, and user friendliness.

In many cases the media itself is not copied or kept on servers, just the small code needed to play it. "The number of operators providing illegal IPTV (Internet Protocol TV) appears to be on the rise and this trend is expected to continue at an accelerated rate in the future...It is known that some European internet users continue to mistakenly take the fact that a digital content service is freely available online without the authorities having taken action as a sign that the service provides legal access to digital content."

The study concluded that the impact of piracy failed to provide stats which suggested a “…displacement of sales by online copyright infringements.” Essentially, piracy does not harm legitimate sales. The report posited that illicit downloads may even bolster legal sales of games and neutral for books and music. The sole area where illegal downloading was found to have a negative impact is with blockbuster films.

Q Quickie

Qatar is the only country that begins with a Q and Iraq is the only country that ends with Q.